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Soliciting Material under §240.14a-12

CF INDUSTRIES HOLDINGS, INC.

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YOUR VOTE IS IMPORTANT!

Remember, you can vote your shares by telephone or via the Internet.

Please follow the easy instructions on the enclosed proxy card.

If you have any questions or need assistance in voting
your shares, please call our proxy solicitor,

INNISFREE M&A INCORPORATED

TOLL-FREE, at 1-888-750-5834.

April 27, 2018

REMINDER TO VOTE YOUR CF SHARES AT ANNUAL MEETING

Dear Fellow CF Industries Employees:

Because many of you are CF Industries shareholders, I wanted to remind you to vote your CF shares on the proposals that will be considered at the company’s Annual Meeting to be held on Thursday, May 10, 2018.

Shareholders will vote on four proposals at the Annual Meeting. CF’s Board of Directors unanimously recommends that you vote “FOR” each of the items.

If you are a CF shareholder and hold your shares through a bank or broker, such as Charles Schwab & Co., you should have already received a notice by email or by standard mail (or both) that contains important instructions for accessing the proxy materials and voting your shares. If you made a previous election to do so, you may have received a printed set of the proxy materials by standard mail, with a proxy card or voting instruction form to record your vote that you can return in the postage-paid envelope included with the printed materials.

Your vote as a shareholder is important. Please vote promptly by following the instructions on the notice, proxy card, or voting instruction form that you received. Voting can be done via the Internet or telephone or, if you received a proxy card, by standard mail. If you have misplaced the information on how to vote or have any questions, please contact Martin Jarosick (mjarosick@cfindustries.com) or Casey Spoden (cspoden@cfindustries.com) in Investor Relations.

Tony Will

President and Chief Executive Officer