Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
HOLMES DARREL LEE
   2. Issuer Name and Ticker or Trading Symbol
Bacterin International Holdings, Inc. [BONE] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
COO
(Last)
(First)
(Middle)
664 CRUISER LANE		 3. Date of Earliest Transaction (Month/Day/Year)
06/10/2014
(Street)

BELGRADE, MT 59714		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 06/10/2014   S   50,000 D $ 0.74 (1) 11,656 D  

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option $ 2.36 07/18/2014   D     70,000   (3) 03/27/2022 Common Stock 70,000 (2) 0 D  
Employee Stock Option $ 1.65 07/18/2014   D     100,000   (4) 09/06/2022 Common Stock 100,000 (2) 0 D  
Employee Stock Option $ 1.34 07/18/2014   D     30,000   (5) 10/09/2016 Common Stock 30,000 (2) 0 D  
Employee Stock Option $ 1.5 07/18/2014   D     18,287 12/29/2009 12/29/2018 Common Stock 18,287 (2) 0 D  
Employee Stock Option $ 1.5 07/18/2014   D     11,712 12/29/2010 12/29/2018 Common Stock 11,712 (2) 0 D  
Employee Stock Option $ 1.5 07/18/2014   D     15,000 12/29/2011 12/29/2018 Common Stock 15,000 (2) 0 D  
Employee Stock Option $ 1.5 07/18/2014   D     15,000 12/29/2012 12/29/2018 Common Stock 15,000 (2) 0 D  
Employee Stock Option $ 1.5 07/18/2014   D     15,000 12/29/2013 12/29/2018 Common Stock 15,000 (2) 0 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
HOLMES DARREL LEE
664 CRUISER LANE
BELGRADE, MT 59714		       COO  

Signatures

 /s/ Darrel Holmes   07/21/2014
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $0.73 to $0.76, inclusive. The reporting person undertakes to provide to Bacterin International Holdings, Inc. ("BONE"), any shareholder of BONE, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
(2) The option was canceled by mutual agreement of the reporting person and the issuer. The reporting person received $1.00 as consideration for the cancellation of all options listed in this Form 4.
(3) The option provided for vesting in five equal annual installments beginning March 27, 2013.
(4) The option provided for vesting in three equal annual installments beginning September 6, 2013.
(5) The option provided for vesting in two equal annual installments beginning 10/9/07.

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