425

FILED BY EXPRESS SCRIPTS, INC.

PURSUANT TO RULE 425 UNDER THE SECURITIES ACT OF 1933

AND DEEMED FILED PURSUANT TO RULE 14a-12

UNDER THE SECURITIES EXCHANGE ACT OF 1934

SUBJECT COMPANY: EXPRESS SCRIPTS, INC.,

ARISTOTLE HOLDING, INC. AND MEDCO HEALTH SOLUTIONS, INC.

COMMISSION FILE NO. 0-20199

Update From George Paz About the Medco Merger

Last week, I had the privilege of spending time in Franklin Lakes, N.J., at the Medco Health Solutions headquarters. A talented group of executives leads Medco and also shares our goal to drive out waste, lower the cost of medications and improve health outcomes.

We’re actively preparing for the future integration of the two companies. While there is a long road ahead, we remain on course to complete our merger in the first half of 2012, pending review by the Federal Trade Commission.

We have been meeting with our counterparts at Medco, and we’ve been very pleased with what we are learning: Medco is truly an innovative organization that is developing novel solutions for clients, doctors and patients. At this point in the process, there are more questions than answers. However, I can confidently say that the combined company will be driven by the same values that brought us here.

When I met with Medco leadership, I wanted to give them a sense of what our company is like and my expectations. The following is what I shared about working at Express Scripts:

Success Is Rewarded. We have a hard-working culture driven by a pay-for-performance philosophy. We have a well-earned reputation for aligning with our clients to ensure they have a high-quality, cost-effective pharmacy benefit. As a result, we make money when we save clients money. When we do this well, we are rewarded.

We Tell It Like It Is. We are straightforward in our communications and committed to being direct, being transparent and operating with unwavering integrity. People may not always like the answers they get, but we believe in honest feedback. That manifests itself in an organization that operates at the highest level of integrity. Our clients expect it, and we demand it of ourselves.

Talent and Passion Win. There is uncertainty that comes with a merger. But let’s be certain about one thing in particular: Talented people who align with our business model and bring a passion for helping patients will have a place at Express Scripts.

Let me add one important reminder: Do not lose your focus. The needs of our clients and members continue to be at the top of our list. Thank you for your continued passion and commitment to the business.

As we move forward, you can expect more communication from me and Senior Staff about our thoughts and observations. We’ll give you an inside look at the various aspects of the integration and provide opportunities for you to share your questions. All of this information will be published on ESInet and archived on the new Merger News website that can be found at the top of the ESInet home page above the stock ticker.

 

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This is an exciting and historic time for our company. We have a lot of work to do, but we remain confident a combined Express Scripts and Medco can do even more to improve the health of American families.

FORWARD-LOOKING STATEMENTS

Cautionary Note Regarding Forward-Looking Statements

This material may include forward-looking statements, both with respect to us and our industry, that reflect our current views with respect to future events and financial performance. Statements that include the words “expect,” “intend,” “plan,” “believe,” “project,” “anticipate,” “will,” “may,” “would” and similar statements of a future or forward-looking nature may be used to identify forward-looking statements. All forward-looking statements address matters that involve risks and uncertainties, many of which are beyond our control. Accordingly, there are or will be important factors that could cause actual results to differ materially from those indicated in such statements and, therefore, you should not place undue reliance on any such statements. We believe that these factors include, but are not limited to, the following:

STANDARD OPERATING FACTORS

 

   

Our ability to remain profitable in a very competitive marketplace is dependent upon our ability to attract and retain clients while maintaining our margins, to differentiate our products and services from others in the marketplace, and to develop and cross sell new products and services to our existing clients;

 

   

Our failure to anticipate and appropriately adapt to changes in the rapidly changing health care industry;

 

   

Changes in applicable laws or regulations, or their interpretation or enforcement, or the enactment of new laws or regulations, which apply to our business practices (past, present or future) or require us to spend significant resources in order to comply;

 

   

Changes to the healthcare industry designed to manage healthcare costs or alter healthcare financing practices;

 

   

Changes relating to our participation in Medicare Part D, the loss of Medicare Part D eligible members, or our failure to otherwise execute on our strategies related to Medicare Part D;

 

   

A failure in the security or stability of our technology infrastructure, or the infrastructure of one or more of our key vendors, or a significant failure or disruption in service within our operations or the operations of such vendors;

 

   

Our failure to effectively execute on strategic transactions, or to integrate or achieve anticipated benefits from any acquired businesses;

 

   

The termination, or an unfavorable modification, of our relationship with one or more key pharmacy providers, or significant changes within the pharmacy provider marketplace;

 

   

The termination, or an unfavorable modification, of our relationship with one or more key pharmaceutical manufacturers, or the significant reduction in payments made or discounts provided by pharmaceutical manufacturers;

 

   

Changes in industry pricing benchmarks;

 

   

Results in pending and future litigation or other proceedings which would subject us to significant monetary damages or penalties and/or require us to change our business practices, or the costs incurred in connection with such proceedings;

 

   

Our failure to execute on, or other issues arising under, certain key client contracts;

 

   

The impact of our debt service obligations on the availability of funds for other business purposes, and the terms and our required compliance with covenants relating to our indebtedness; our failure to attract and retain talented employees, or to manage succession and retention for our Chief Executive Officer or other key executives;

 

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TRANSACTION-RELATED FACTORS

 

   

Uncertainty as to whether Express Scripts, Inc. (Express Scripts) will be able to consummate the transaction with Medco Health Solutions, Inc. (Medco) on the terms set forth in the merger agreement;

 

   

The ability to obtain governmental approvals of the transaction with Medco;

 

   

Uncertainty as to the actual value of total consideration to be paid in the transaction with Medco;

 

   

Failure to realize the anticipated benefits of the transaction, including as a result of a delay in completing the transaction or a delay or difficulty in integrating the businesses of Express Scripts and Medco;

 

   

Uncertainty as to the long-term value of Express Scripts Holding Company (currently known as Aristotle Holding, Inc.) common shares;

 

   

Limitation on the ability of Express Scripts and Express Scripts Holding Company to incur new debt in connection with the transaction;

 

   

The expected amount and timing of cost savings and operating synergies; and

 

   

Failure to receive the approval of the stockholders of either Express Scripts or Medco for the transaction.

The foregoing review of important factors should not be construed as exhaustive and should be read in conjunction with the other cautionary statements that are included herein and elsewhere, including the risk factors included in Express Scripts’ most recent reports on Form 10-K and Form 10-Q and the risk factors included in Medco’s most recent reports on Form 10-K and Form 10-Q and other documents of Express Scripts, Express Scripts Holding Company and Medco on file with the Securities and Exchange Commission ("SEC"). Any forward-looking statements made in this material are qualified in their entirety by these cautionary statements, and there can be no assurance that the actual results or developments anticipated by us will be realized or, even if substantially realized, that they will have the expected consequences to, or effects on, us or our business or operations. Except to the extent required by applicable law, we undertake no obligation to update publicly or revise any forward-looking statement, whether as a result of new information, future developments or otherwise.

ADDITIONAL INFORMATION AND WHERE TO FIND IT

This communication is not a solicitation of a proxy from any stockholder of Express Scripts, Medco or Express Scripts Holding Company. In connection with the Agreement and Plan of Merger among Medco, Express Scripts, Express Scripts Holding Company, Plato Merger Sub Inc. and Aristotle Merger Sub, Inc. (the “Merger”), Medco, Express Scripts and Express Scripts Holding Company, filed relevant materials with the SEC, including a Registration Statement on Form S-4 filed by Express Scripts Holding Company that contains a joint proxy statement/prospectus. INVESTORS AND SECURITY HOLDERS ARE URGED TO READ THESE MATERIALS BECAUSE THEY CONTAIN IMPORTANT INFORMATION ABOUT MEDCO, EXPRESS SCRIPTS, EXPRESS SCRIPTS HOLDING COMPANY AND THE MERGER. The Form S-4, including the joint proxy statement/prospectus, and other relevant materials and any other documents filed by Express Scripts, Express Scripts Holding Company or Medco with the SEC, may be obtained free of charge at the SEC’s web site at www.sec.gov. In addition, investors and security holders may obtain free copies of the documents filed with the SEC by directing a written request to:

Mackenzie Partners, Inc.

105 Madison Avenue

New York, New York 10016

 

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This communication shall not constitute an offer to sell or the solicitation of an offer to buy any securities, nor shall there be any sale of securities in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such jurisdiction. No offering of securities shall be made except by means of a prospectus meeting the requirements of Section 10 of the Securities Act of 1933, as amended.

PARTICIPANTS IN THE SOLICITATION

Express Scripts, Express Scripts Holding Company and Medco and their respective executive officers and directors may be deemed to be participants in the solicitation of proxies from the security holders of either Express Scripts and Medco in connection with the Merger. Information about Express Scripts’ directors and executive officers is available in Express Scripts’ definitive proxy statement, dated March 21, 2011, for its 2011 annual general meeting of stockholders. Information about Medco’s directors and executive officers is available in Medco’s definitive proxy statement, dated April 8, 2011, for its 2011 annual general meeting of stockholders. Other information regarding the participants and description of their direct and indirect interests, by security holdings or otherwise, is contained in the Form S-4 and the joint proxy statement/prospectus regarding the Merger that Express Scripts Holding Company filed with the SEC.

 

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