UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(AMENDMENT NO. 2)*
Alexion Pharmaceuticals, Inc.
--------------------------------------------------------------------------------
(Name of Issuer)
Common Stock, $.0001 Par Value Per Share
--------------------------------------------------------------------------------
(Title of Class of Securities)
01531109
--------
(CUSIP Number)
December 31, 2005
-----------------
(Date of Event which Requires Filing
of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:
[ ] Rule 13d-1(b)
[X] Rule 13d-1(c)
[ ] Rule 13d-1(d)
*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities,
and for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.
The information required on the remainder of this cover page shall not be
deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 ("Act") or otherwise subject to the liabilities of that section of
the Act but shall be subject to all other provisions of the Act (however, see
the Notes).
Page 1 of 10
-------------------------- -------------------
CUSIP No. 01531109 13G Page 2 of 10 Pages
-------------------------- -------------------
---------- --------------------------------------------------------------------
1 NAME OF REPORTING PERSON
I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
S.A.C. Capital Advisors, LLC
---------- --------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
(a) |_|
(b) |X|
---------- --------------------------------------------------------------------
3 SEC USE ONLY
---------- --------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
--------------------- ----- ---------------------------------------------------
5 SOLE VOTING POWER
0
NUMBER OF ----- ---------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED 3,000 (see Item 4)
BY ----- ---------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0
WITH ----- ---------------------------------------------------
8 SHARED DISPOSITIVE POWER
3,000 (see Item 4)
---------- --------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
3,000 (see Item 4)
---------- --------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
|_|
---------- --------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
Less than 0.1% (see Item 4)
---------- --------------------------------------------------------------------
12 TYPE OF REPORTING PERSON*
00
---------- --------------------------------------------------------------------
*SEE INSTRUCTION BEFORE FILLING OUT
Page 2 of 10
-------------------------- -------------------
CUSIP No. 01531109 13G Page 3 of 10 Pages
-------------------------- -------------------
---------- --------------------------------------------------------------------
1 NAME OF REPORTING PERSON
I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
S.A.C. Capital Management, LLC
---------- --------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
(a) |_|
(b) |X|
---------- --------------------------------------------------------------------
3 SEC USE ONLY
---------- --------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
-------------------- ------ ---------------------------------------------------
5 SOLE VOTING POWER
0
NUMBER OF ------ ---------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED 3,000 (see Item 4)
BY ------ ---------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0
WITH ------ ---------------------------------------------------
8 SHARED DISPOSITIVE POWER
3,000 (see Item 4)
---------- --------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
3,000 (see Item 4)
---------- --------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
|_|
---------- --------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
Less than 0.1% (see Item 4)
---------- --------------------------------------------------------------------
12 TYPE OF REPORTING PERSON*
00
---------- --------------------------------------------------------------------
*SEE INSTRUCTION BEFORE FILLING OUT
Page 3 of 10
-------------------------- -------------------
CUSIP No. 01531109 13G Page 4 of 10 Pages
-------------------------- -------------------
---------- --------------------------------------------------------------------
1 NAME OF REPORTING PERSON
I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Sigma Capital Management, LLC
---------- --------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
(a) |_|
(b) |X|
---------- --------------------------------------------------------------------
3 SEC USE ONLY
---------- --------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
-------------------- ------ ---------------------------------------------------
5 SOLE VOTING POWER
0
NUMBER OF ------ ---------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED 0 (see Item 4)
BY ------ ---------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0
WITH ------ ---------------------------------------------------
8 SHARED DISPOSITIVE POWER
0 (see Item 4)
---------- --------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
0 (see Item 4)
---------- --------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
|_|
---------- --------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
0% (see Item 4)
---------- --------------------------------------------------------------------
12 TYPE OF REPORTING PERSON*
00
---------- --------------------------------------------------------------------
*SEE INSTRUCTION BEFORE FILLING OUT
Page 4 of 10
-------------------------- -------------------
CUSIP No. 01531109 13G Page 5 of 10 Pages
-------------------------- -------------------
---------- --------------------------------------------------------------------
1 NAME OF REPORTING PERSON
I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Steven A. Cohen
---------- --------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
(a) |_|
(b) |X|
---------- --------------------------------------------------------------------
3 SEC USE ONLY
---------- --------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
-------------------- ------ ---------------------------------------------------
5 SOLE VOTING POWER
0
NUMBER OF ------ ---------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED 3,000 (see Item 4)
BY ------ ---------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0
WITH ------ ---------------------------------------------------
8 SHARED DISPOSITIVE POWER
3,000 (see Item 4)
---------- --------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
3,000 (see Item 4)
---------- --------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
|_|
---------- --------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
Less than 0.1% (see Item 4)
---------- --------------------------------------------------------------------
12 TYPE OF REPORTING PERSON*
IN
---------- --------------------------------------------------------------------
*SEE INSTRUCTION BEFORE FILLING OUT
Page 5 of 10
ITEM 1(A) NAME OF ISSUER:
--------------
Alexion Pharmaceuticals, Inc.
ITEM 1(B) ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:
-----------------------------------------------
352 Knotter Drive
Cheshire, Connecticut 06410
ITEMS 2(A) NAME OF PERSON FILING:
----------------------
This statement is filed by: (i) S.A.C.
Capital Advisors, LLC, ("SAC Capital
Advisors") with respect to shares of common
stock, $.0001 par value per share ("Shares")
of the Issuer beneficially owned by S.A.C.
MultiQuant Fund, LLC ("SAC MultiQuant") and
S.A.C. Arbitrage Fund, LLC ("SAC Arbitrage
Fund"); (ii) S.A.C. Capital Management, LLC,
("SAC Capital Management") with respect to
Shares beneficially owned by SAC MultiQuant;
(iii) Sigma Capital Management, LLC ("Sigma
Capital Management"); and (iv) Steven A.
Cohen with respect to Shares beneficially
owned by SAC Capital Advisors, SAC Capital
Management and SAC MultiQuant.
ITEM 2(B) ADDRESS OF PRINCIPAL BUSINESS OFFICE:
-------------------------------------
The address of the principal business office
of (i) SAC Capital Advisors and Mr. Cohen is
72 Cummings Point Road, Stamford,
Connecticut 06902 and (ii) SAC Capital
Management and Sigma Capital Management is
540 Madison Avenue, New York, New York
10022.
ITEM 2(C) CITIZENSHIP:
------------
SAC Capital Advisors, SAC Capital Management
and Sigma Capital Management are Delaware
limited liability companies. Mr. Cohen is a
United States citizen.
ITEM 2(D) TITLE OF CLASS OF SECURITIES:
-----------------------------
Common Stock, par value $.0001 per share
Page 6 of 10
ITEM 2(E) CUSIP NUMBER:
-------------
01531109
ITEM 3 Not Applicable
ITEM 4 OWNERSHIP:
----------
The percentages used herein are calculated
based upon the Shares issued and outstanding
as of November 30, 2005 as reported on the
Issuer's quarterly report on Form 10-Q filed
with the Securities and Exchange Commission
by the Company for the quarterly period
ended October 31, 2005.
1. S.A.C. Capital Advisors, LLC
(a) Amount beneficially owned: 3,000
(b) Percent of class: Less than 0.1%
(c)(i) Sole power to vote or direct the vote: -0-
(ii) Shared power to vote or direct the vote: 3,000
(iii) Sole power to dispose or direct the disposition: -0-
(iv) Shared power to dispose or direct the disposition: 3,000
2. S.A.C. Capital Management, LLC
(a) Amount beneficially owned: 3,000
(b) Percent of class: Less than 0.1%
(c)(i) Sole power to vote or direct the vote: -0-
(ii) Shared power to vote or direct the vote: 3,000
(iii) Sole power to dispose or direct the disposition: -0-
(iv) Shared power to dispose or direct the disposition: 3,000
3. Sigma Capital Management, LLC
(a) Amount beneficially owned: -0-
(b) Percent of class: 0%
(c)(i) Sole power to vote or direct the vote: -0-
(ii) Shared power to vote or direct the vote: -0-
(iii) Sole power to dispose or direct the disposition: -0-
(iv) Shared power to dispose or direct the disposition: -0-
4. Steven A. Cohen
(a) Amount beneficially owned: 3,000
(b) Percent of class: Less than 0.1%
(c)(i) Sole power to vote or direct the vote: -0-
Page 7 of 10
(ii) Shared power to vote or direct the vote: 3,000
(iii) Sole power to dispose or direct the disposition: -0-
(iv) Shared power to dispose or direct the disposition: 3,000
SAC Capital Advisors, SAC Capital Management, Sigma Capital
Management, and Mr. Cohen own directly no Shares. Pursuant to
investment agreements, each of SAC Capital Advisors and SAC
Capital Management share all investment and voting power with
respect to the securities held by SAC MultiQuant. Pursuant to
an investment management agreement, Sigma Capital Management
maintains investment and voting power with respect to the
securities held by Sigma Capital Associates. Mr. Cohen
controls each of SAC Capital Advisors, SAC Capital Management
and Sigma Capital Management. By reason of the provisions of
Rule 13d-3 of the Securities Exchange Act of 1934, as amended,
each of (i) SAC Capital Advisors, SAC Capital Management and
Mr. Cohen may be deemed to own beneficially 3,000 Shares
(constituting Less than 0.1% of the Shares outstanding). Each
of SAC Capital Advisors, SAC Capital Management and Mr. Cohen
disclaim beneficial ownership of any of the securities covered
by this statement.
ITEM 5 OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS:
--------------------------------------------
If this statement is being filed to report the fact that as of
the date hereof the reporting person has ceased to be the
beneficial owner of more than five percent of the class of
securities, check the following. |X|
ITEM 6 OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON:
---------------------------------------------------------------
Not Applicable
ITEM 7 IDENTIFICATION AND CLASSIFICATION OF THE
SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING
REPORTED ON BY THE PARENT HOLDING COMPANY:
----------------------------------------
Not Applicable
ITEM 8 IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP:
----------------------------------------------------------
Not Applicable
Page 8 of 10
ITEM 9 NOTICE OF DISSOLUTION OF GROUP:
------------------------------
Not Applicable
ITEM 10 CERTIFICATION:
--------------
By signing below the signatory certifies that, to the best of his
knowledge and belief, the securities referred to above were not acquired and are
not held for the purpose of or with the effect of changing or influencing the
control of the issuer of the securities and were not acquired and are not held
in connection with or as a participant in any transaction having that purpose or
effect.
Page 9 of 10
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.
Dated: February 14, 2006
S.A.C. CAPITAL ADVISORS, LLC
By: /s/ Peter Nussbaum
---------------------------------
Name: Peter Nussbaum
Title: Authorized Person
S.A.C. CAPITAL MANAGEMENT, LLC
By: /s/ Peter Nussbaum
---------------------------------
Name: Peter Nussbaum
Title: Authorized Person
SIGMA CAPITAL MANAGEMENT, LLC
By: /s/ Peter Nussbaum
---------------------------------
Name: Peter Nussbaum
Title: Authorized Person
STEVEN A. COHEN
By: /s/ Peter Nussbaum
---------------------------------
Name: Peter Nussbaum
Title: Authorized Person
Page 10 of 10